|Retinoblastoma (Rb) survival rate has improved significantly in recent years in high-income countries, but remain guarded in low- and middle-income countries, where the majority of global Rb disease burden lies. A significant factor, playing a pivotal role in this disparity, is the disease stage at which children present to local Rb centers.
To address this issue in a global scale, a network was formed, including clinicians from all across the world dedicated to the management of Rb, and a study titled Global Retinoblastoma Presentation 2017 was designed. The aim of this retrospective analysis is to document the presentation mode of treatment-naïve Rb patients that presented to local centers during 2017. Currently there are over 3,000 patients enrolled, which represent nearly 1/2 of the estimated global incidence of Rb during a calendar year.