Dear Colleagues, It is our great pleasure to invite you to join The 19th International Symposium on Pediatric Neuro-Oncology (ISPNO 2020). ISPNO is the most prominent international scientific meeting for pediatric neuro-oncology. ISPNO 2020 will be held at Karuizawa Prince Hotel West between December 13 (Sun) – 16 (Wed), 2020. ISPNO 2020 is a hybrid meeting, and you have a choice to attend in-person onsite or remotely online. In the Main Program, we have a fantastic line-up of 80 invited lecturers who will give a live talk and Q&A either onsite or online, which will be broadcasted by live streaming. The live streaming contents will be recorded and posted in the On-Demand Program after the symposium. In the On-Demand Program, all 858 accepted abstracts and 13 Education Day lectures will be made viewable from December 13, 2020 until February 13, 2021 for all registrants. You will find more details on our website (http://ispno2020.umin.jp). This is the first ever hybrid meeting for ISPNO. It is a great opportunity to watch the lectures by the world’s experts and gain access to the latest results of research/clinical trials of pediatric neuro-oncology from your home or workplace without having to travel. You are also most welcome to join in-person in Karuizawa if you could! And don’t miss out the Welcome Message from our ISPNO 2020 lecturers! https://www.youtube.com/watch?v=tWFbaV_Um30 Make sure to watch till the end to see how we made the video... Please register now to join ISPNO 2020. We offer a very competitive registration fee for virtual and in-person participation. The success of ISPNO 2020 depends upon your support! http://ispno2020.umin.jp/registration/index.html We look forward to welcoming you to ISPNO 2020 in Karuizawa, in person or virtually!